PROPRIETARY NAME AND DOSAGE FORM
F10 GERMICIDAL TREATMENT SHAMPOO (pour on) Registration No.: Act 36/1947 G3107, APVMA 58543, VMD Schedule 6 SAES:GMP M7586 WDA 32613.
COMPOSITION
Quaternary Ammonium Compounds
SPECIES
For use on pet animals including rabbits, ferrets and small rodents including hamsters, guinea pigs, mice and rats.
INDICATIONS
A dermatological preparation effective against bacteria and fungi as a skin treatment and to prevent re-infestation. For example the following bacterial conditions (Pyotraumatic Dermatitis, Superficial Pyoderma, Skin Fold Dermatitis), yeast (Malasseziasis) and fungal conditions (Dermatophytosis). Also available with long acting insecticide to repel insects.
ANTIMICROBIAL ACTION
The antimicrobial action of the preparation is based upon the proprietary branded F10 compound. The mechanism of action of F10 is derived from those of each component taken separately, in addition to those due to the additive synergistic action of all components combined. At the concentrations in the product F10 has been assessed as giving a >log5 reduction in microbial counts against gram positive and gram negative bacteria: fungi, yeasts and moulds. The group of keratinophylic fungi is very large, but only two generally known as dermatophytes, are known to cause disease (“ringworm”) in animals. The genera involved are Microsporum spp, and Trichophyton spp. At the concentration in the product F10 GERMICIDAL TREATMENT SHAMPOO was found to be effective in a contact time of at least 15 minutes, however three repeat treatments applied every other day is the recommended treatment protocol.
DOSAGE AND DIRECTIONS FOR USE
- Use only as directed
- Wet the hair thoroughly. Initially a preliminary application of F10 GERMICIDAL TREATMENT SHAMPOO may be necessary to break through the natural oils on the hair. Should this be necessary work the shampoo into the coat and then rinse off and re-apply immediately.
- Apply F10 GERMICIDAL TREATMENT SHAMPOO and work into a good lather. Leave for at least 15 to 20 minutes then thoroughly rinse off with clean water.
- A recommended infection control programme for use in cases of contagious skin infections is shown.
- Replace cap after use.
TOXICOLOGY
Acute toxicity studies were carried out in accordance with the test requirements as specified by the EPA. All studies were subject to an independent GLP compliance audit.
| Toxicity Test | F10 Germicidal Treatment Shampoo | Category |
| Oral Toxicity (rats) | >2000 to 5000mg/kg | Category III |
| Dermal Toxicity (rats) | >5000mg/kg | Category III |
| Dermal Irritation (guinea pigs) | Zero at 24 hrs (very slight erytherma (grade 1) but reversible within 24 hrs) | Category IV |
| Eye irritation (rabbits) | Zero at 24 hrs (cornea and iris showed no reaction. The eyelids and nictating membranes were graded 1 after 1 hour and were reversible after 72 hrs) | Category IV |
| Skin sensitization (guinea pigs) | No sensitization | |
PRECAUTIONS
- Ingestion: DO NOT induce vomiting. Give water to drink.
- Eye contact: Rinse eyes with water, seek medical advice if necessary.
WARNINGS
- Do not mix with soaps and other chemicals.
- Avoid contact with eyes.
- Keep out of reach of children, uninformed persons and pets.
- Although this remedy has been extensively tested under a large variety of conditions, failure thereof may ensure as a result of a wide range of reasons. If this is suspected, seek veterinary advice and notify the registration holder.
IDENTIFICATION
F10 GERMICIDAL TREATMENT SHAMPOO
Clear straw coloured liquid with a herbal odour.
PRESENTATION
A liquid in 250ml HDPE bottles
STORAGE INSTRUCTIONS
Store below 30°C in dry conditions
SHELF LIFE
3 Years
RECOMMENDATIONS FOR USE IN CASES OF CONTAGIOUS SKIN INFECTIONS
| APPLICATION | FREQUENCY | DILUTION/10 LITRES | MINIMUM EXPOSURE |
| HOUSING Isolate all diagnosed and visibly infected animals immediately. Infected puppies must be isolated with the mother. |
|||
| Remove all bedding and equipment (e.g. toys, brushes, water and feed bowls) from cages, floors. |
|||
| Soak bedding and equipment in F10CL or F10CLXD before washing. Hang to dry / tumble dry. | Daily | 500 ml | 15 min |
| Wash water and feed bowls with warm water and F10CLXD, spray with F10CL and leave to dry. | Daily | 500 ml | Leave to dry |
| Wash all surfaces (work benches, floors, tables, walls, tiles) with F10CLXD | Daily | 500 ml | Leave to dry |
| STAFF Handling of animals should be limited and involve as few people as possible. |
|||
| Staff movement must be restricted to designated areas. | |||
| Infected animals and areas should be handled last to avoid cross-contamination. | |||
| Protective clothing should be worn and discarded or washed and disinfected with F10CL or F10CLXD daily. | Daily | 500 ml | Soak 15 min, hang to dry |
| Proper hand decontamination (running water, F10 Hand Scrub and paper towel to dry or use F10 Hand Gel) must be done after any animals or possibly infected material such as bedding had been handled | In between handling animals | 4 ml as is | 30 sec |
| GENERAL Grass should be kept short and exposed to as much sun as possible. |
|||
| Carrier boxes must be washed (F10CLXD) and disinfected (F10CL) after every use and left to dry. | After every use | 500 ml | Leave to dry |
| All cleaning equipment (mops, cloths, brushes) must be washed with F10CLXD and disinfected with F10CL at the end of each day. | At the end of each shift | 500 ml | Hang to dry |
| ANIMAL TREATMENT
Wash all animals immediately with F10 Germicidal Treatment Shampoo to prevent the disease from spreading. |
As is | Leave 15 min rinse | |
| Repeat for up to 3 treatments on every other day on infected animals and once a week on non-infected animals. | As is | Leave 15 min rinse | |
| Apply F10 Germicidal Barrier Ointment to affected lesions once daily. Remove all organic material and ointment using an approved irrigation solution before re-applying the ointment. | Every other day or as prescribed by veterinarian | As is | Leave to dry |