PROPRIETARY NAME & SIZES
F1OCL VETERINARY DISINFECTANT
(liquid, dilute as directed 5L, 1L RTU)
(Reg. No. G3076, Act 36/1947) (NRCS/8054/276279/266)
F1OCLXD VETERINARY DISINFECTANT/CLEANSER
(liquid, dilute as directed 5L)
(Reg. No. G3077, Act 36/1947)
F10 SKIN PREP SOLUTION
(liquid, use as is, in 5L)
(Reg No G 3105, Act 36/1947)
F10 ODOUR ELIMINATOR
(liquid, use as is in 250ml and 500ml , dilute as directed in the 5 L)
(Reg No NRCS/8054/276279/314)
F10 DISINFECTANT AEROSOL & AEROSOL FOGGER
(500ml aerosol pressurised dispensing canister, use as is)
(Reg No NRCS/8054/276279/315)
F10 WIPES
(100 impregnated cellulose tissues)
(Reg No NRCS/8054/276279/316)
COMPOSITION
The core actives of all the disinfectant products are quaternary ammonium compound, with non toxic ampholytic surfactants and sequestrants.
| LEVEL OF ACTIVES | OTHER | pH* |
| F1OCL VETERINARY DISINFECTANT | ||
| QAC 10,7g/L | Ampholytic surfactants and sequestrants Water to balance |
7.5 |
| F10 DISINFECTANT RTU | ||
| QAC 0,21 g/L | Ampholytic surfactants, sequestrants/detergents Fragrance Water to balance |
7.5 |
| F1OCLXD VETERINARY DISINFECTANT/CLEANSER | ||
| QAC 10,7g/L | Ampholytic surfactants, sequestrants/detergents Fragrance Water to balance |
7.5 |
| F10 SKIN PREP SOLUTION | ||
| QAC 0,44g/L | Ampholytic surfactants and sequestrants Alcohol 20% Water to balance |
6.5 |
| F10 ODOUR ELIMINATOR | ||
| QAC 0,21g/L | Ampholytic surfactants and sequestrants Fragrance Water to balance |
5.9 |
| F10 AEROSOL DISINFECTANT | ||
| QAC 0,83g/L | Ampholytic surfactants and sequestrants propellant | 7.5 |
| F10 WIPES AND SACHETS | ||
| QAC 0,43g/L | Ampholytic surfactants and sequestrants | 7.5 |
* The pH value refers to the packed concentration
INDICATIONS
A broad spectrum biocide effective against bacteria, fungi, viruses and bacterial and fungal spores is indicative of those shown below:-
| BACTERIA (gram positive and gram negative (spp) |
FUNGI, YEASTS and MOULDS (spp) |
VIRUSES (enveloped and non-enveloped) |
SPORES (bacterial and fungal) spp |
|
| Acinetobacter | Listeria | Aspergillus | Adenovirus | Aspergillus |
| Campylobacter | MRSA | Candida | Avian Influenza H5N2 HPA1 |
Bacillus |
| Chlamydophila | Mycobacterium | Microsporum | Canineparvovirus | Microsporum |
| Clostridium | Mycoplasma | Penicillium | Circovirus | Penicillium |
| Cholera | Micrococcus | Trichophyton | Enterovirus | Trichophyton |
| Corynebacterium | Ornitobacteriun Rhinotracheale |
Foot and Mouth Disease | ||
| Citrobacter | Pasteurella | Feline Herpesvirus | ||
| Entercoccus | Proteus vulgaris | Hepatitis B | ||
| Enterobacter | Pseudomonas | HIV | ||
| Escherichia coli | Salmonella | IBD | ||
| Klebsiella | Staphylococcus | Newcastle Disease | ||
| Leptospira | Streptococcus | Rabies | ||
*FMDV is effectively eliminated with the pH buffered product F10CL General Farm Disinfectant
APPLICATIONS
The core product F1OCL VETERINARY DISINFECTANT is a high performance surface acting biocidal compound and due to its inherently low toxicity and low irritation characteristics is widely used within the veterinary profession in companion and large animal practices, referral hospitals, zoo’s, laboratories, and various other institutions. It is used in numerous applications, i.e. cold sterilisation of instruments and equipment including endoscopes, intravenous catheters, and endotracheal tubes; high level disinfection of hard surfaces and air spaces, water treatment, and as a sanitising rinse for solid food and fruit. Fogging with F10CL VETERINARY DISINFECTANT, (a spray of fine mist-like droplets) has been shown to be 100% effective in eliminating airborne microorganisms.
F10 DISINFECTANT PRODUCTS (F10 ANTISEPTIC SOLUTION which is authorised by the VMD* and FDA**) for use in aerosol fogging applications in the presence of animals as well as a number of clinical applications including nebulising in respiratory tract Aspergillosis infections, wound irrigation, and nasal flushing.
*VMD Schedule 6,SAES , **FDA MUMS Index.
F10 DISINFECTANT RTU is a 1:50 pre-diluted solution of F10CL Veterinary Disinfectant for HLD (high level disinfection).
F1OCLXD VETERINARY DISINFECTANT/CLEANSER is used for hard surface disinfection and cleaning of lightly soiled areas such as kennels and cages.
F10 SKIN PREP SOLUTION is a pre-op skin decontaminant.
F10 ODOUR ELIMINATOR is a hard surface and aerosol high level disinfectant with a masking pine fragrance.
F10 AEROSOL DISINFECTANT is available with on/off and total evacuation actuators for use as a hard surface and air space disinfectant. Tests have shown that aerosol disinfection is an effective method of carrying out high level disinfection of air spaces.
F10 WIPES are a disinfectant impregnated surface wipe for use on equipment such as thermometers, and for hand decontamination when washing facilities are unavailable.
ANTIMICROBIAL ACTION
The antimicrobial action mechanism of the F10 branded disinfectants is taken from each component separately but in addition is due to the additive synergistic action of all components combined.
Bactericidal tests have been carried out in accordance with EN1276 having a performance pass criteria of log3 reduction in microbial counts, the AFNOR Standard (French) which is a log4 reduction in microbial counts, the European Union EN Standard which is a log5 reduction in microbial counts, and the AOAC Standard (USA) which is a log6 (1,000,000 times) reduction in microbial counts. MIC in-vitro tests have shown significant depth of performance as indicated. Generally testing was carried out at ambient temperatures with the exception of EN Standard tests where some were carried out at low temperatures 10°C. The EN Standard for low temperatures is 10°C and at this temperatures bactericidal performance was equal to that at ambient temperatures. Other tests carried out at elevated temperatures of 45°C showed a significant increase in performance.
FIGURE A: THE F10CL MIC VALUES
| Test organism | Concentration of F1OCL (dilution) that resulted in complete visual inhibition of the Test organism = MIC value |
| Pseudomonas aeruginosa -ATCC 27853 | A dilution of 1/200 or 0,5 % F1OCL |
| Escherichia coli – ATCC 25922 | A dilution of 1/800 or 0,125 % F1OCL |
| Staphylococcus aureus -ATCC 25923 | A dilution of 1/3200 or 0,03125 % F1OCL |
| Klebsiella pneumoniae – ATCC 10031 | A dilution of 1/800 or 0,125 % F1OCL |
| Staphylococcus aureus – MRSA Local isolate | A dilution of 1/3200 or 0,03125 % F1OCL |
| Pasteurella multocida – Local isolate | A dilution of 1/3200 or 0,03125 % F1OCL |
| Enterococcus faecalis – ATCC 29212 | A dilution of 1/3200 or 0,03125 % F1OCL |
| Salmonella choleraesuis, Serotype typhimurium – ATCC 13311 | A dilution of 1/1600 or 0,0625 % F1OCL |
Fungicidal tests have been carried out in accordance with EN1650 and EN1657, AFNOR and EN Standards which require a log5 and log4 reduction in microbial counts respectively.
Virucidal tests have been carried out in accordance with various internationally accepted protocols by the UP Faculty of Veterinary Science’s Department of Poultry Diseases, and the Department of Veterinary Tropical Diseases; the ARC – Onderstepoort Veterinary Institute. Test requirements called for log4 and log5 reduction in microbial counts.
Sporicidal tests have been carried out in accordance with EN 13704-2002 (log3 ), 13697-2001, and 1650-1997 Standards which required a log5 reduction in microbial counts.
CONCENTRATIONS AND CONTACT TIMES
Concentrations and contact times are indicated on each product label. It should be noted that additional tests were carried out to determine various speed of kill rates to meet varying application demands.
Bactericidal test standard contact times are generally 5 minutes. However it was found that a log3 reduction in gram positive bacteria was achieved in 30 seconds and similarly 60 seconds for gram negative bacteria all at a concentration of 1:100 of the F10 CL Veterinary Disinfectant. In the AOAC test a log6 reduction was achieved in both gram positive and gram negative bacteria in a 10 minutes contact time.
Fungi in the vegetative state, yeasts and moulds were eliminated in 30 seconds at a concentration of 1:100 of F10CL Veterinary Disinfectant.
Enveloped viruses were inactivated at 1:100 in 10 minutes whereas the more resistant non-enveloped viruses required a concentration of up to 1:20 with a contact time of 10 minutes to achieve the same reduction.
Bacterial and fungal spores log5 reduction could be achieved in 5 minutes at a concentration of 1:20 or using 1:50 in 15 minutes with F10CL Veterinary Disinfectant.
DOSAGE AND DIRECTIONS FOR USE
For F10CL VETERINARY DISINFECTANTS clear away debris and rinse surfaces, then apply as below:
- Environmental general disinfection dilute 1:100
- High level disinfection (including fungal spores) dilute 1:50
- Resistant viruses (e.g. parvovirus) dilute 1:25
- Sterilisation of instruments/equipment dilute 1:20
Additional information is available in application user guidelines. Other products refer to each specific product label.
TOXICICOLOGY OF F10 CL DISINFECTANT AT HIGHEST AS USED CONCENTRATION
Studies were carried out by a GLP laboratory in accordance with OECD and EPA guidelines.
Information on toxicological effects
| Toxicity | USE DILUTIONS (1:20 and higher) |
| Acute Oral Toxicity: (Rat) | No toxicity |
| Acute Dermal Toxicity: (Rat) | No toxicity |
| Acute Eye Irritation | None |
| Acute Dermal Irritation | None |
| Acute Inhalation Toxicity | None |
| Skin Sensitization | Not a skin sensitizer |
| Carcinogenicity, mutagenicity and toxicity for reproduction |
Based on data for the raw materials, no carcinogenic, mutagenic or toxicity for reproduction is predicted |
Ecological information
| Aquatic Toxicity | Fish | Not available |
| Aquatic Toxicity | Algae | Not available |
| Aquatic Toxicity | Daphnia | Not available |
Residual toxicity
Five-week supervised trial using day-old broiler chicks restricted to 1:200 and 1:50 solutions of F10CL in drinking water showed no F10 residual build-up in muscle meat, liver or kidneys.
PERSISTENCE AND DEGRADABILITY
For practical purpose the in-use product is biodegradable.
BIOACCUMULATIVE POTENTIAL
No known adverse effects from normal use.
MOBILITY IN SOIL Immobile in soil.
CORROSION
The F10 Veterinary Disinfectants are non-corrosive at the recommended dilutions (complies with SANS 636 on polished aluminium strip after 30 days).
FREE RINSING
All F10CL Veterinary Disinfectants are free rinsing at recommended dilutions (complies with SABS test 1593).
WATER INSOLUBLE MATTER CONTENT
The water insoluble matter content of F10CL Veterinary Disinfectants and F10 Skin Prep Solution is 0,3g/litre (complies with SABS 1593).
PRECAUTIONSAND WARNINGS —see product labels
REGISTRATION HOLDER
Health and Hygiene (Pty) Ltd. PO Box 906, Florida Hills, 1716, South Africa.
MANUFACTURED BY
Health and Hygiene (Pty) Ltd in accordance with GMP (Good Manufacturing Practice) license reference M-7586 issued by APVMA.


